Molecular characterization of Cryptosporidium from various hosts

被引：128

作者：

Morgan, UM ^{[1
]}

Sargent, KD

Deplazes, P

Forbes, DA

Spano, F

Hertzberg, H

Elliot, A

Thompson, RCA

机构：

[1] Murdoch Univ, Div Vet & Biomed Sci, State Agr Biotechnol Ctr, Murdoch, WA 6150, Australia

[2] WHO, Collaborating Ctr Mol Epidemiol Parasit Infect, Geneva, Switzerland

[3] Univ Zurich, Inst Parasitol, CH-8057 Zurich, Switzerland

[4] Univ Western Australia, Princess Margaret Hosp, Dept Paediat, Perth, WA 6001, Australia

[5] Univ Rome La Sapienza, Ist Parassitol, I-00185 Rome, Italy

来源：

PARASITOLOGY | 1998年 / 117卷

关键词：

Cryptosporidium; characterization; genotypes;

D O I：

10.1017/S0031182098002765

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

A 298 bp region of the Cryptosporidium parvum 18S rDNA and a 390 bp region of the acetyl-CoA synthetase gene were sequenced for a range of human and animal isolates of Cryptosporidium from different geographical areas. A distinct genotype is common to isolates from cattle, sheep and goats and also an alpaca from Peru and is referred to here as the 'calf'-derived Cryptosporidium genotype. Another genotype of 'human'-derived isolates also appears to be conserved amongst human isolates although humans are also susceptible to infection-with the 'calf' Cryptosporidium genotype. Mice and pigs carry genetically distinct genotypes of Cryptosporidium. Three snake isolates were also analysed, 2 of which exhibited C. muris genotypes and the third snake isolate carried a distinct 'mouse' genotype.

引用

页码：31 / 37

页数：7

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