Protonated chiral catalysts: Versatile tools for asymmetric synthesis

被引：225

作者：

Bolm, C ^{[1
]}

Rantanen, T ^{[1
]}

Schiffers, I ^{[1
]}

Zani, L ^{[1
]}

机构：

[1] Rhein Westfal TH Aachen, Inst Organ Chem, D-52056 Aachen, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 12期

关键词：

asymmetric catalysis; Bronsted acids; hydrogen bonds; organocatalysis; protonation;

D O I：

10.1002/anie.200500154

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Acid treatment: Exposure of catalytically inactive (neutral) molecules to strong Brønsted acids generates cationic species (e.g. 1 and 2) that catalyze a wide range of synthetically powerful transformations. These reactions give products with excellent ee values. TfO- = trifluoromethanesulfonate; TFA = trifluoroacetic acid. © 2005 Wiley-VCH Verlag GmbH &. Co. KGaA.

引用

页码：1758 / 1763

页数：6

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