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Membrane receptors for soluble defense collagens

被引：94
作者：
Tenner, AJ [1 ]
机构：
[1] Univ Calif Irvine, Dept Biochem & Mol Biol, Irvine, CA 92697 USA
来源：
CURRENT OPINION IN IMMUNOLOGY | 1999年 / 11卷 / 01期
关键词：
D O I：
10.1016/S0952-7915(99)80007-7
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Membrane receptors for the soluble 'defense collagens' naturally occurring chimeric molecules that contain a recognition domain contiguous with a collagen-like triple helical domain and play a role in protecting the host from pathogens entering the blood, lung and other tissues - are being isolated. These receptors are key to understanding the mechanisms by which defense collagens influence cellular responses in order to either provide rapid 'stealth clearance' of cellular debris or to initiate the responses that lead to the destruction of harmful microbes.
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页码：34 / 41
页数：8
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