The para-toluenesulfonic acid-promoted synthesis of 2-substituted benzoxazoles and benzimidazoles from diacylated precursors.

被引：63

作者：

DeLuca, MR ^{[1
]}

Kerwin, SM ^{[1
]}

机构：

[1] UNIV TEXAS,COLL PHARM,DIV MED CHEM,AUSTIN,TX 78712

来源：

TETRAHEDRON | 1997年 / 53卷 / 02期

关键词：

D O I：

10.1016/S0040-4020(96)01009-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of benzoxazoles and benzimidazoles is accomplished by treating N,O-diacylated 2-aminophenols or N,N'-diacylated 1,2-phenylenediamines with p-toluenesulfonic acid under reflux in xylenes or toluene. These reactions are operationally simple and proceed in excellent yield. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：457 / 464

页数：8

共 29 条

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