Micronutrients in pregnancy

被引:170
作者
Black, RE [1 ]
机构
[1] Johns Hopkins Univ, Sch Publ Hlth, Dept Int Hlth, Baltimore, MD 21205 USA
关键词
pregnancy; fetal growth; vitamins; minerals; trace elements; low birth weight; micronutrients;
D O I
10.1079/BJN2000314
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Vitamins and minerals, referred to collectively as micronutrients, have important influences on the health of pregnant women and the growing fetus. Iron deficiency results in anemia which may increase the risk of death from hemorrhage during delivery, but its effects on fetal development and birth outcomes is still unclear. Folic acid deficiency can lead to hematological consequences, pregnancy complications and congenital malformations, but again the association with other birth outcomes is equivocal. Zinc deficiency has been associated in some, but not all studies with complications of pregnancy and delivery, as well as with growth retardation, congenital abnormalities and retarded neurobehavioral and immunological development in the fetus. Iodine deficiency during pregnancy results in cretinism and possible fetal wastage and preterm delivery. Deficiency of other minerals such as magnesium, selenium, copper, and calcium have also been associated with complications of pregnancy, childbirth or fetal development. Deficiencies of vitamins other than folate may likewise be related to such complications; and vitamin A or beta -carotene supplements in pregnancy reduced maternal mortality by 50 % in a controlled trial in Nepal. Additional research is need on the prevalence of such deficiencies and their consequences and on cost-effective public health interventions for their control.
引用
收藏
页码:S193 / S197
页数:5
相关论文
共 49 条
[1]  
ACC/SCN, 1992, 2 ACCSCN, V1
[2]  
Allen LH, 1997, NUTR REV, V55, P91, DOI 10.1111/j.1753-4887.1997.tb06460.x
[3]  
[Anonymous], 1991, Lancet, V338, P131, DOI 10.1016/0140-6736(91)90133-A
[4]  
ARNAUD J, 1994, EUR J CLIN NUTR, V48, P341
[5]  
Azaïs-Braesco V, 2000, AM J CLIN NUTR, V71, p1325S, DOI 10.1093/ajcn/71.5.1325s
[6]   REDUCTION OF INCIDENCE OF PREMATURITY BY FOLIC ACID SUPPLEMENTATION IN PREGNANCY [J].
BAUMSLAG, N ;
EDELSTEIN, T ;
METZ, J .
BMJ-BRITISH MEDICAL JOURNAL, 1970, 1 (5687) :16-+
[7]  
Beard JL, 2000, AM J CLIN NUTR, V71, p1288S, DOI 10.1093/ajcn/71.5.1288s
[8]   Potential contribution of maternal zinc supplementation during pregnancy to maternal and child survival [J].
Caulfield, LE ;
Zavaleta, N ;
Shankar, AH ;
Merialdi, M .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1998, 68 (02) :499S-508S
[9]   Maternal zinc supplementation does not affect size at birth or pregnancy duration in Peru [J].
Caulfield, LE ;
Zavaleta, N ;
Figueroa, A ;
Leon, Z .
JOURNAL OF NUTRITION, 1999, 129 (08) :1563-1568
[10]   Effect of antioxidants on the occurrence of pre-eclampsia in women at increased risk: a randomised trial [J].
Chappell, LC ;
Seed, PT ;
Briley, AL ;
Kelly, FJ ;
Lee, R ;
Hunt, BJ ;
Parmar, K ;
Bewley, SJ ;
Shennan, AH ;
Steer, PJ ;
Poston, L .
LANCET, 1999, 354 (9181) :810-816