Proteomics of multiprotein complexes: answering fundamental questions in neuroscience

被引:36
作者
Grant, SGN [1 ]
Husi, H [1 ]
机构
[1] Univ Edinburgh, Dept Neurosci, Edinburgh EH9 3JQ, Midlothian, Scotland
关键词
D O I
10.1016/S0167-7799(01)01799-1
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Proteomics tools offer new ways to analyse networks of proteins that control important neurobiological phenomena such as learning and memory. In this review, we discuss how a combined proteomic, pharmacological and genetic approach reveals that multiprotein complexes process neural information and encode memories. Simultaneous analysis of multiple proteins enables the development of new concepts and approaches for neuroscience research.
引用
收藏
页码:S49 / S54
页数:6
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