Understanding mild persistent asthma in children: The next frontier

被引:23
作者
Bisgaard, H [1 ]
Szefler, SJ
机构
[1] Univ Copenhagen Hosp, Danish Paediat Asthma Ctr, Dept Paediat, DK-2900 Copenhagen, Denmark
[2] Natl Jewish Ctr Immunol & Resp Med, Dept Pediat, Denver, CO 80206 USA
关键词
children; adolescents; persistent asthma; mild;
D O I
10.1016/j.jaci.2004.11.018
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Limitations in asthma prevalence studies and difficulties in diagnosing pediatric asthma lead to uncertainty over the full extent of mild persistent asthma in children and adolescents. Although recent surveys have reported that the majority of pediatric patients with asthma in the United States and Europe have symptoms consistent with mild disease, these surveys have limitations in design. Thus, the true prevalence of mild asthma remains unknown. It is unclear whether children with mild persistent asthma progress to more severe asthma, but the risk of severe asthma exacerbations seems to be unrelated to the symptom severity. Clinical studies restricted to pediatric patients with mild asthma are limited, but available data do suggest substantial morbidity of mild persistent asthma in this population and support inhaled corticosteroid intervention. There is a need for further investigation into the true prevalence of mild persistent asthma in children and adolescents, and optimal treatment.
引用
收藏
页码:708 / 713
页数:6
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