Enantiospecific syntheses of pseudopterosin aglycones.: Part 1.: Synthesis of the putative aglycone of pseudopterosin G-J via an A→AB→ABC annulation strategy

被引：26

作者：

Chow, R ^{[1
]}

Kocienski, PJ

Kuhl, A

LeBrazidec, JY

Muir, K

Fish, P

机构：

[1] Univ Leeds, Dept Chem, Leeds LS2 9JT, W Yorkshire, England

[2] Univ Glasgow, Dept Chem, Glasgow G12 8QQ, Lanark, Scotland

[3] Pfizer Ltd, Cent Res, Sandwich CT13 9NJ, Kent, England

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 2001年 / Royal Society of Chemistry卷 / 19期

关键词：

D O I：

10.1039/b102960f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The putative aglycone of pseudopterosin G-J and its enantiomer were synthesised enantio specifically from 2,3-dimethoxytoluene and eta (3)-allyl cationic complexes of molybdenum and iron respectively. The A --> AB --> ABC annulation strategy entailed the use of allyl cations or their equivalents for the creation of the three benzylic stereogenic centres. The X-ray structure of tetrahydro naphthalene (-)-41a was determined.

引用

页码：2344 / 2355

页数：12

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