Do disparate mechanisms of duplication add similar genes to the genome?

被引：73

作者：

Davis, JC ^{[1
]}

Petrov, DA ^{[1
]}

机构：

[1] Stanford Univ, Dept Biol Sci, Stanford, CA 90305 USA

来源：

TRENDS IN GENETICS | 2005年 / 21卷 / 10期

关键词：

D O I：

10.1016/j.tig.2005.07.008

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Gene duplication is the fundamental source of new genes. Biases in duplication have profound implications for the dynamics of gene content during evolution. In this article, we compare genes arising from whole gene duplication (WGD), smaller scale duplication (SSD) and singletons in Saccharomyces cerevisiae. Our results demonstrate that genes duplicated by WGD and SSD are similarly biased with respect to codon bias and evolutionary rate, although differing significantly in their functional constituency.

引用

页码：548 / 551

页数：4

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