Isolated diffuse mesangial sclerosis and Wilms tumor suppressor gene

被引：17

作者：

Ito, S

Takata, A

Hataya, H

Ikeda, M

Kikuchi, H

Hata, J

Honda, M

机构：

[1] Tokyo Metropolitan Kiyose Childrens Hosp, Dept Nephrol, Tokyo, Japan

[2] Keio Univ, Sch Med, Dept Pathol, Tokyo 160, Japan

来源：

JOURNAL OF PEDIATRICS | 2001年 / 138卷 / 03期

关键词：

D O I：

10.1067/mpd.2001.111317

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Diffuse mesangial sclerosis is a rare renal disease, occurring either in isolation or as part of Denys-Drash syndrome. Denys-Drash syndrome originates from mutations of the Wilms tumor suppressor gene (WT1). We describe the presence of WT1 mutations in 7 Japanese children with isolated diffuse mesangial sclerosis.

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收藏

页码：425 / 427

页数：3

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