Fibroblast biology - Development and differentiation of synovial fibroblasts in arthritis

被引：58

作者：

Edwards, JCW ^{[1
]}

机构：

[1] UCL Ctr Rheumatol, London W1P 9PG, England

来源：

ARTHRITIS RESEARCH | 2000年 / 2卷 / 05期

关键词：

embryology; hyaluronan; synoviocyte; synovium; vascular cell adhesion molecule-1;

D O I：

10.1186/ar110

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Synovial fibroblasts occur as two phenotypes - intimal and subintimal. The specialised intimal phenotype includes expression of uridine diphosphoglucose dehydrogenase (UDPGD), vascular cell adhesion molecule-1 (VCAM-1) and complement decay-accelerating factor (DAF). These gene products contribute to specialised functions relating to tissue movement and leucocyte traffic.

引用

页码：344 / 347

页数：4

共 33 条

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