DCC and netrins

被引：118

作者：

Culotti, JG ^{[1
]}

Merz, DC

机构：

[1] Univ Toronto, Fac Med, Dept Mol & Med Genet, Toronto, ON M5S 1A8, Canada

[2] Mt Sinai Hosp, Samuel Lunenfeld Res Inst, Toronto, ON M5G 1X5, Canada

来源：

CURRENT OPINION IN CELL BIOLOGY | 1998年 / 10卷 / 05期

关键词：

D O I：

10.1016/S0955-0674(98)80036-7

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Recent advances highlight the versatility and complexity of this highly conserved axon and cell migration guidance system. Characterization of netrin mutant phenotypes in worm, fly and mouse all suggest that netrins play local as well as long-range roles in guidance. Evidence from multiple sources also indicates that the netrin receptor DCC can mediate both attractive and repulsive responses to netrins.

引用

页码：609 / 613

页数：5

共 39 条

[1] The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein
Ackerman, SL
Kozak, LP
Przyborski, SA
Rund, LA
Boyer, BB
Knowles, BB
[J]. NATURE, 1997, 386 (6627) : 838 - 842
[2] Antebi A, 1998, DEVELOPMENT, V125, P1191
[3] Deleted in colorectal carcinoma (DCC) binds heparin via its fifth fibronectin type III domain
Bennett, KL
Bradshaw, J
Youngman, T
Rodgers, J
Greenfield, B
Aruffo, A
Linsley, PS
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (43) : 26940 - 26946
[4] UNC-40, a C-elegans homolog of DCC (Deleted in Colorectal Cancer), is required in motile cells responding to UNC-6 netrin cues
Chan, SSY
Zheng, H
Su, MW
Wilk, R
Killeen, MT
Hedgecock, EM
Culotti, JG
[J]. CELL, 1996, 87 (02) : 187 - 195
[5] THE AXONAL CHEMOATTRACTANT NETRIN-1 IS ALSO A CHEMOREPELLENT FOR TROCHLEAR MOTOR AXONS
COLAMARINO, SA
TESSIERLAVIGNE, M
[J]. CELL, 1995, 81 (04) : 621 - 629
[6] Suppressors of ectopic UNC-5 growth cone steering identify eight genes involved in axon guidance in Caenorhabditis elegans
Colavita, A
Culotti, JG
[J]. DEVELOPMENTAL BIOLOGY, 1998, 194 (01) : 72 - 85
[7] Switching of the coupling of the beta(2)-adrenergic receptor to different G proteins by protein kinase A
Daaka, Y
Luttrell, LM
Lefkowitz, RJ
[J]. NATURE, 1997, 390 (6655) : 88 - 91
[8] Netrin-1 and DCC mediate axon guidance locally at the optic disc: Loss of function leads to optic nerve hypoplasia
Deiner, MS
Kennedy, TE
Fazeli, A
Serafini, T
TessierLavigne, M
Sretavan, DW
[J]. NEURON, 1997, 19 (03) : 575 - 589
[9] DELETORRE JR, 1997, NEURON, V19, P1211
[10] Desai CJ, 1997, DEVELOPMENT, V124, P1941

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