Bisphosphonates as anticancer drugs

被引：100

作者：

Mundy, GR ^{[1
]}

Yoneda, T ^{[1
]}

机构：

[1] Univ Texas, Hlth Sci Ctr, San Antonio, TX 78284 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 1998年 / 339卷 / 06期

关键词：

D O I：

10.1056/NEJM199808063390609

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：398 / 400

页数：3

共 15 条

[1] In vitro cytoreductive effects on multiple myeloma cells induced by bisphosphonates [J].

Aparicio, A ;

Gardner, A ;

Tu, Y ;

Savage, A ;

Berenson, J ;

Lichtenstein, A .

LEUKEMIA, 1998, 12 (02) :220-229

[2] Efficacy of pamidronate in reducing skeletal events in patients with advanced multiple myeloma [J].

Berenson, JR ;

Lichtenstein, A ;

Porter, L ;

Dimopoulos, MA ;

Bordoni, R ;

George, S ;

Lipton, A ;

Keller, A ;

Ballester, O ;

Kovacs, MJ ;

Blacklock, HA ;

Bell, R ;

Simeone, J ;

Reitsma, DJ ;

Heffernan, M ;

Seaman, J ;

Knight, RD .

NEW ENGLAND JOURNAL OF MEDICINE, 1996, 334 (08) :488-493

[3]

Boissier S, 1997, CANCER RES, V57, P3890

[4] Reduction in new metastases in breast cancer with adjuvant clodronate treatment [J].

Diel, IJ ;

Solomayer, EF ;

Costa, SD ;

Gollan, C ;

Goerner, R ;

Wallwiener, D ;

Kaufmann, M ;

Bastert, G .

NEW ENGLAND JOURNAL OF MEDICINE, 1998, 339 (06) :357-363

[5]

FLEISCH H, 1997, OVERVIEW BISPHOSPH S

[6] Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis [J].

Guise, TA ;

Yin, JJ ;

Taylor, SD ;

Kumagai, Y ;

Dallas, M ;

Boyce, BF ;

Yoneda, T ;

Mundy, GR .

JOURNAL OF CLINICAL INVESTIGATION, 1996, 98 (07) :1544-1549

[7] Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone metastases [J].

Hortobagyi, GN ;

Theriault, RL ;

Porter, L ;

Blayney, D ;

Lipton, A ;

Sinoff, C ;

Wheeler, H ;

Simeone, JF ;

Seaman, J ;

Knight, RD ;

Heffernan, M ;

Reitsma, DJ .

NEW ENGLAND JOURNAL OF MEDICINE, 1996, 335 (24) :1785-1791

[8]

HUGHES DE, 1995, J BONE MINER RES, V10, P1478

[9] Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras [J].

Luckman, SP ;

Hughes, DE ;

Coxon, FP ;

Russell, RGG ;

Rogers, MJ .

JOURNAL OF BONE AND MINERAL RESEARCH, 1998, 13 (04) :581-589

[10] MODULATION OF TYPE-BETA TRANSFORMING GROWTH-FACTOR ACTIVITY IN BONE CULTURES BY OSTEOTROPIC HORMONES [J].

PFEILSCHIFTER, J ;

MUNDY, GR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (07) :2024-2028

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