Hypercortisolemia and depression

被引:266
作者
Gillespie, CF [1 ]
Nemeroff, CB [1 ]
机构
[1] Emory Univ, Sch Med, Dept Psychiat & Behav Sci, Atlanta, GA 30322 USA
来源
PSYCHOSOMATIC MEDICINE | 2005年 / 67卷
关键词
depression; hypercortisolemia; cortisol; corticotropin-releasing factor; dexamethasone;
D O I
10.1097/01.psy.0000163456.22154.d2
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Hypercortisolemia and dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis are often found in severe forms of depression. The authors review the history of techniques used to assess the functions of the HPA axis, evidence for hypercortisolemia as a state rather than trait component of depression, and treatment implications.
引用
收藏
页码:S26 / S28
页数:3
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