Acute Arboviral Infections in Guinea, West Africa, 2006

被引：50

作者：

Jentes, Emily S. ^{[1
,2
]}

Robinson, Jaimie ^{[4
]}

Johnson, Barbara W. ^{[4
]}

Conde, Ibrahima ^{[5
]}

Sakouvougui, Yosse ^{[5
]}

Iverson, Jennifer ^{[4
]}

Beecher, Shanna ^{[4
]}

Bah, M. Alpha ^{[5
]}

Diakite, Fousseny ^{[5
]}

Coulibaly, Mamadi ^{[5
]}

Bausch, Daniel G. ^{[3
]}

机构：

[1] Ctr Dis Control & Prevent, Epidem Intelligence Serv, Off Workforce & Career Dev, Atlanta, GA 30333 USA

[2] Ctr Dis Control & Prevent, Div Global Migrat & Quarantine, Atlanta, GA 30333 USA

[3] Tulane Sch Publ Hlth & Trop Med, Dept Trop Med, New Orleans, LA USA

[4] Ctr Dis Control & Prevent, Div Vector Borne Infect Dis, Ft Collins, CO USA

[5] NZerekore Reg Hosp, Ctr Int Rech Infect Trop, Nzerekore, Guinea

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 2010年 / 83卷 / 02期

关键词：

REPUBLIC-OF-GUINEA; CHIKUNGUNYA-VIRUS; SEROLOGICAL INVESTIGATIONS; HEMORRHAGIC-FEVER; MOSQUITOS DIPTERA; FEBRILE PATIENTS; NILE-VIRUS; DENGUE; SENEGAL; CAMEROON;

D O I：

10.4269/ajtmh.2010.09-0688

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Acute febrile illnesses comprise the majority of the human disease burden in sub-Saharan Africa We hypothesized that arboviruses comprised a considerable proportion of undiagnosed febrile illnesses in Guinea and sought to determine the frequency of arboviral disease in two hospitals there. Using a standard case definition, 47 suspected cases were detected in approximately 4 months Immunoglobulin M antibody capture enzyme-linked immunosorbent assays and plaque-reduction neutralization assays revealed that 63% (30/47) of patients were infected with arboviruses. including 11 West Nile. 2 yellow fever, 1 dengue, 8 chikungunya. and 5 Tahyna infections. Except for yellow fever, these are the first reported cases of human disease from these viruses in Guinea and the first reported cases of symptomatic Tahyna infection in Africa These results strongly suggest that arboviruses circulate and are common causes of disease in Guinea Improving surveillance and laboratory capacity for arbovirus diagnoses will be integral to understanding the burden posed by these agents in the region.

引用

页码：388 / 394

页数：7

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