An efficient synthetic approach to aza-C-glycosyl compounds. Application to the synthesis of an aza-C-disaccharide

被引：60

作者：

Martin, OR

Liu, L

Yang, F

机构：

[1] Department of Chemistry, State University of New York, Binghamton

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 12期

关键词：

D O I：

10.1016/0040-4039(96)00226-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The NIS-mediated cyclization of aminoheptenitols 5-8 (prepared in three steps from tetra-O-benzyl-D-hexopyranoses) provided 1,2,6-trideoxy-2,6-imino-l-iodoheptitol derivatives 9-12, respectively, highly stereoselectively and in high yield. The ''alpha-D-gluco'' epimer 9 was used in the synthesis of a precursor of an aza-C-disaccharide and its reaction with triethyl phosphite was investigated.

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页码：1991 / 1994

页数：4

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