Genomics for Disease Treatment and Prevention

被引:27
作者
Bloss, Cinnamon S. [2 ]
Jeste, Dilip V. [3 ]
Schork, Nicholas J. [1 ,2 ]
机构
[1] Scripps Res Inst, Dept Mol & Expt Med, La Jolla, CA 92037 USA
[2] Scripps Translat Sci Inst, La Jolla, CA 92037 USA
[3] Univ Calif San Diego, Dept Pychiat & Neurosci, Sam & Rose Stein Inst Res Aging, San Diego, CA 92093 USA
关键词
Genomics; Genetic testing; Genetic risk assessment; Public health genomics; Pharmacogenomics; MONOZYGOTIC TWINS CONCORDANT; GENE-EXPRESSION; PERSONALIZED MEDICINE; UNIPOLAR DEPRESSION; ALZHEIMERS-DISEASE; MAJOR DEPRESSION; WIDE ASSOCIATION; SWEDISH TWINS; HUMAN OBESITY; US FDA;
D O I
10.1016/j.psc.2010.11.005
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
The enormous advances in genetics and genomics of the past decade have the potential to revolutionize health care, including mental health care, and bring about a system predominantly characterized by the practice of genomic and personalized medicine. This article briefly reviews the history of genetics and genomics and assesses the extent to which the results of genetic and genomic studies are currently being leveraged clinically for disease treatment and prevention. Relevant social, economic, and policy issues relevant to genomic medicine are also reviewed, and priority research areas in which further work is needed are identified.
引用
收藏
页码:147 / +
页数:21
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