Safety and Efficacy of Therapies for Skin Symptoms of Psoriasis in Patients with Psoriatic Arthritis: A Systematic Review

被引：17

作者：

Boehncke, Wolf-Henning ^{[1
]}

Martinez, David Alvarez ^{[1
]}

Solomon, James A. ^{[2
,3
,4
]}

Gottlieb, Alice B. ^{[5
]}

机构：

[1] Univ Hosp Geneva, Dept Dermatol, CH-1211 Geneva 14, Switzerland

[2] Ameriderm Res, Ormond Beach, FL USA

[3] Univ Cent Florida, Coll Med, Orlando, FL 32816 USA

[4] Univ Illinois, Coll Med, Urbana, IL 61801 USA

[5] Tufts Med Ctr, Boston, MA USA

来源：

JOURNAL OF RHEUMATOLOGY | 2014年 / 41卷 / 11期

关键词：

PSORIASIS; PSORIATIC ARTHRITIS; THERAPY; EFFICACY; PSORIASIS AREA AND SEVERITY INDEX; PLACEBO-CONTROLLED TRIAL; SEVERE PLAQUE PSORIASIS; DOUBLE-BLIND; PHASE-II; CERTOLIZUMAB PEGOL; CLINICAL-TRIAL; CYCLOSPORINE-A; METHOTREXATE; MODERATE; MULTICENTER;

D O I：

10.3899/jrheum.140880

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Numerous guidelines and recommendations exist for the treatment of psoriasis in various populations. One important population is patients with psoriatic arthritis (PsA) who have symptoms of both joint and skin disease. In patients with both facets of psoriatic disease, skin and joints must be treated separately, but also simultaneously. As several systemic therapies are approved for either one or both, the concept of treating both facets with the same drug is feasible. This review summarizes evidence from studies in patients with PsA on the efficacy of these drugs on psoriatic skin disease in these patients.

引用

页码：2301 / 2305

页数：5

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