Saccharin as a salt former. Enhanced solubilities of saccharinates of active pharmaceutical ingredients

被引：141

作者：

Bhatt, PM

Ravindra, NV

Banerjee, R

Desiraju, GR ^{[1
]}

机构：

[1] Univ Hyderabad, Sch Chem, Hyderabad 500046, Andhra Pradesh, India

[2] GVK BIOSCIENCES Private Ltd, Informat Div, Hyderabad 500016, Andhra Pradesh, India

来源：

CHEMICAL COMMUNICATIONS | 2005年 / 08期

关键词：

D O I：

10.1039/b416137h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Saccharin, acting as a weak acid, forms salts with basic APIs and these salts have the desirable property of enhanced water solubility.

引用

页码：1073 / 1075

页数：3

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