The acyl glucuronide metabolite of mycophenolic acid inhibits the proliferation of human mononuclear leukocytes

被引：82

作者：

Shipkova, M ^{[1
]}

Wieland, E ^{[1
]}

Schütz, E ^{[1
]}

Wiese, C ^{[1
]}

Niedmann, PD ^{[1
]}

Oellerich, M ^{[1
]}

Armstrong, VW ^{[1
]}

机构：

[1] Univ Gottingen, Zentrum Innere Med, Klin Chem Abt, D-37075 Gottingen, Germany

来源：

TRANSPLANTATION PROCEEDINGS | 2001年 / 33卷 / 1-2期

关键词：

D O I：

10.1016/S0041-1345(00)02424-6

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：1080 / 1081

页数：2

共 13 条

[1]

Bailey MJ, 1998, CHEM-BIOL INTERACT, V115, P153

[2] Clinical pharmacokinetics of mycophenolate mofetil [J].

Bullingham, RES ;

Nicholls, AJ ;

Kanmm, BR .

CLINICAL PHARMACOKINETICS, 1998, 34 (06) :429-455

[3]

DAYTON JS, 1992, MOL PHARMACOL, V41, P671

[4]

NOWAK I, 1995, CLIN CHEM, V41, P1011

[5] Genotoxicity of acyl glucuronide metabolites formed from clofibric acid and gemfibrozil: A novel role for Phase-II-mediated bioactivation in the hepatocarcinogenicity of the parent aglycones? [J].

Sallustio, BC ;

Harkin, LA ;

Mann, MC ;

Krivickas, SJ ;

Burcham, PC .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 1997, 147 (02) :459-464

[6]

Schütz E, 1999, CLIN CHEM, V45, P419

[7] Analysis, pharmacokinetics and therapeutic drug monitoring of mycophenolic acid [J].

Shaw, LM ;

Korecka, M ;

Van Breeman, R ;

Nowak, I ;

Brayman, KL .

CLINICAL BIOCHEMISTRY, 1998, 31 (05) :323-328

[8] Identification of glucoside and carboxyl-linked glucuronide conjugates of mycophenolic acid in plasma of transplant recipients treated with mycophenolate mofetil [J].

Shipkova, M ;

Armstrong, VW ;

Wieland, E ;

Niedmann, PD ;

Schütz, E ;

Brenner-Weiss, G ;

Voihsel, M ;

Braun, F ;

Oellerich, M .

BRITISH JOURNAL OF PHARMACOLOGY, 1999, 126 (05) :1075-1082

[9]

Shipkova M, 2000, CLIN CHEM, V46, P365

[10] 2'-DEOXYGUANOSINE TOXICITY FOR B-LYMPHOID AND MATURE T-LYMPHOID CELL-LINES IS MEDIATED BY GUANINE RIBONUCLEOTIDE ACCUMULATION [J].

SIDI, Y ;

MITCHELL, BS .

JOURNAL OF CLINICAL INVESTIGATION, 1984, 74 (05) :1640-1648

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