What age trajectories of cumulative deficits and medical costs tell us about individual aging and mortality risk: Findings from the NLTCS-Medicare data

被引:21
作者
Yashin, Anatoli I. [1 ]
Arbeev, Konstantin G. [1 ]
Kulminski, Alexander [1 ]
Akushevich, Igor [1 ]
Akushevich, Lucy [1 ]
Ukraintseva, Svetlana V. [1 ]
机构
[1] Duke Univ, Ctr Populat Hlth & Aging, Durham, NC 27708 USA
关键词
cumulative deficits; medical costs; mortality; quadratic hazard model; stress resistance;
D O I
10.1016/j.mad.2007.12.005
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
An important feature of aging-related deterioration in human health is the decline in organisms' resistance to stresses, which contributes to an increase in morbidity and mortality risks. In human longitudinal studies of aging, such a decline is not measured directly, so indirect methods of statistical modeling have to be used for evaluating this characteristic. Since medical interventions reflect severity of occurring health disorders, data from Medicare service use files can be used for such modeling. In this paper, we use the National Long Term Care Survey (NLTCS) data merged with the Medicare service use files to investigate dynamics of stress resistance in the U.S. elderly. We constructed individual indices of cumulative deficits and medical costs and investigated their separate and joint effects on dynamics of mortality risks using the quadratic hazard model (QHM). We found that males show a faster decline in stress resistance with age than females. (C) 2007 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:191 / 200
页数:10
相关论文
共 31 条
[1]   NEW LOOK AT STATISTICAL-MODEL IDENTIFICATION [J].
AKAIKE, H .
IEEE TRANSACTIONS ON AUTOMATIC CONTROL, 1974, AC19 (06) :716-723
[2]  
[Anonymous], 2004, EVOL PSYCHOL-US
[3]   Mathematical models for human cancer incidence rates [J].
Arbeev, KG ;
Ukraintseva, SV ;
Arbeeva, LS ;
Yashin, AI .
DEMOGRAPHIC RESEARCH, 2005, 12 :237-271
[4]  
Bhattacharya J, 2004, NBER FR HLTH POL RES, P75
[5]  
BROWN ML, 2002, MED CARE, P40
[6]   Gender differences in risk taking: A meta-analysis [J].
Byrnes, JP ;
Miller, DC ;
Schafer, WD .
PSYCHOLOGICAL BULLETIN, 1999, 125 (03) :367-383
[7]   Just what defines frailty? [J].
Fisher, AL .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2005, 53 (12) :2229-2230
[8]   The network and the remodeling theories of aging:: historical background and new perspectives [J].
Franceschi, C ;
Valensin, S ;
Bonafè, M ;
Paolisso, G ;
Yashin, AI ;
Monti, D ;
De Benedictis, C .
EXPERIMENTAL GERONTOLOGY, 2000, 35 (6-7) :879-896
[9]  
GOLDMAN DP, 2005, HLTH AFFAIRS S2, V24
[10]   Medicare beneficiaries' costs of care in the last year of life [J].
Hogan, C ;
Lunney, J ;
Gabel, J ;
Lynn, J .
HEALTH AFFAIRS, 2001, 20 (04) :188-195