Banff 07 classification of renal allograft pathology: Updates and future directions

被引：1586

作者：

Solez, K. ^{[1
]}

Colvin, R. B. ^{[2
,3
]}

Racusen, L. C. ^{[4
]}

Haas, M. ^{[4
]}

Sis, B. ^{[1
,5
]}

Mengeld, M. ^{[5
]}

Halloran, P. F. ^{[5
]}

Baldwin, W. ^{[4
]}

Banfi, G. ^{[6
]}

Collins, A. B. ^{[2
,3
]}

Cosio, F. ^{[7
]}

David, D. S. R. ^{[8
,9
]}

Drachenberg, C. ^{[10
]}

Einecke, G. ^{[5
]}

Fogo, A. B. ^{[11
]}

Gibson, I. W. ^{[12
]}

Glotz, D. ^{[13
]}

Iskandar, S. S. ^{[14
]}

Kraus, E. ^{[15
]}

Lerut, E. ^{[16
]}

Mannon, R. B. ^{[17
]}

Mihatsch, M. ^{[18
]}

Nankivell, B. J. ^{[19
]}

Nickeleit, V. ^{[20
]}

Papadimitriou, J. C.

Randhawa, P. ^{[21
]}

Regele, H. ^{[22
]}

Renaudin, K. ^{[23
]}

Roberts, I. ^{[24
]}

Seron, D. ^{[25
]}

Smith, R. N. ^{[2
,3
]}

Valente, M. ^{[26
]}

机构：

[1] Univ Alberta, Dept Lab Med & Pathol, Edmonton, AB, Canada

[2] Massachusetts Gen Hosp, Boston, MA 02114 USA

[3] Harvard Univ, Sch Med, Dept Pathol, Cambridge, MA 02138 USA

[4] Johns Hopkins Univ, Dept Pathol, Baltimore, MD USA

[5] Univ Alberta, Dept Med, Div Nephrol & Immunol, Alberta Transplant Appl Genom Ctr, Edmonton, AB, Canada

[6] IRCCS, Fdn Osped Maggiore, Div Nephrol, Milan, Italy

[7] Mayo Clin & Mayo Fdn, Div Nephrol & Hypertens, Rochester, MN 55905 USA

[8] Univ Sao Paulo, Div Pathol, BR-05508 Sao Paulo, Brazil

[9] Univ Sao Paulo, Renal Transplant Unit, BR-05508 Sao Paulo, Brazil

[10] Univ Maryland, Dept Pathol, Baltimore, MD 21201 USA

[11] Vanderbilt Univ, Sch Med, Dept Pathol, Nashville, TN 37212 USA

[12] Univ Manitoba, Dept Pathol, Winnipeg, MB R3T 2N2, Canada

[13] Hosp St Louis, Dept Nephrol, Paris, France

[14] Wake Forest Univ, Bowman Gray Sch Med, Dept Pathol, Winston Salem, NC 27103 USA

[15] Johns Hopkins Univ, Dept Nephrol, Baltimore, MD USA

[16] Univ Hosp Leuven, Dept Morphol & Mol Pathol, Louvain, Belgium

[17] Natl Inst Digest & Kidney Dis, NIH, Transplantat Branch, Bethesda, MD USA

[18] Univ Basel, Inst Pathol, Basel, Switzerland

[19] Westmead Hosp, Ctr Transplant Res & Renal Res, Sydney, NSW, Australia

[20] Univ N Carolina, Dept Pathol & Lab Med, Chapel Hill, NC USA

[21] Univ Pittsburgh, Dept Pathol, Div Transplantat Pathol, Pittsburgh, PA USA

[22] Univ Vienna, Inst Pathol, A-1010 Vienna, Austria

[23] CHU Hotel Dieu, Dept Pathol, Nantes, France

[24] John Radcliffe Hosp, Dept Cellular Pathol, Oxford OX3 9DU, England

[25] Univ Bellvitge, Dept Nephrol, Barcelona, Spain

[26] Univ Padua, Dept Med Diag Sci, Padua, Italy

来源：

AMERICAN JOURNAL OF TRANSPLANTATION | 2008年 / 8卷 / 04期

关键词：

acute allograft rejection; acute cellular rejection; acute rejection; allograft rejection; antibody-mediated rejection; Banff; Banff lesions; Banff schema; classification; chronic allograft nephropathy; chronic allograft rejection; genomic markers; GeneChip;

D O I：

10.1111/j.1600-6143.2008.02159.x

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

The 9th Banff Conference on Allograft Pathology was held in La Coruna, Spain on June 23-29, 2007. A total of 235 pathologists, clinicians and scientists met to address unsolved issues in transplantation and adapt the Banff schema for renal allograft rejection in response to emerging data and technologies. The outcome of the consensus discussions on renal pathology is provided in this article. Major updates from the 2007 Banff Conference were: inclusion of peritubular capillaritis grading, C4d scoring, interpretation of C4d deposition without morphological evidence of active rejection, application of the Banff criteria to zero-time and protocol biopsies and introduction of a new scoring for total interstitial inflammation (ti-score). In addition, emerging research data led to the establishment of collaborative working groups addressing issues like isolated 'v' lesion and incorporation of omics-technologies, paving the way for future combination of graft biopsy and molecular parameters within the Banff process.

引用

页码：753 / 760

页数：8

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