Detection of virulence associated genes in clinical strains of Vibrio mimicus

被引:12
作者
Bi, KW [1 ]
Miyoshi, S [1 ]
Tomochika, K [1 ]
Shinoda, S [1 ]
机构
[1] Okayama Univ, Fac Pharmaceut Sci, Okayama 7008530, Japan
关键词
Vibrio mimicus; virulence associated genes; polymerase chain reaction;
D O I
10.1111/j.1348-0421.2001.tb01292.x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
A total of 42 clinical strains of Vibrio mimicus were examined for the presence of virulence associated genes toxR, toxS, toxT, tcpP, ctx and tcpA by PCR assay. Almost all strains were shown to have the toxR gene, while the toxS gene was found in 27 strains. On the other hand, five strains possessed both toxT and tcpP genes, but others had neither. Only two strains were positive for amplification of the ctx gene, whereas no PCR product with tcpA primers was detected. The results indicate the incomplete copies of virulence cascade in V mimicus strains. The pathogenesis and epidemic potential of this species is also discussed.
引用
收藏
页码:613 / 616
页数:4
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