Constructing linkage maps in autotetraploid species using simulated annealing

被引:26
作者
Hackett, CA [1 ]
Pande, B [1 ]
Bryan, GJ [1 ]
机构
[1] Scottish Crop Res Inst, Biomath & Stat Scotland, Dundee DD2 5DE, Scotland
关键词
autotetraploid; potato; ordering; simulated annealing;
D O I
10.1007/s00122-002-1164-1
中图分类号
S3 [农学(农艺学)];
学科分类号
0901 ;
摘要
In this paper we demonstrate how molecular markers segregating in a full-sib autotetraploid mapping population can be ordered to form a linkage map using simulated annealing. This approach facilitates the examination of orders close to the optimum to see which marker placings are fixed and identify the markers whose position is loss certain. A simulation study investigates the effects of population size, marker spacing, ratio of dominant to codominant markers, typing errors and missing values. The method is applied to map 30 amplified fragment length polymorphism and microsatellite markers on linkage group IV of potato.
引用
收藏
页码:1107 / 1115
页数:9
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