Organ allocation in lung transplant

被引:68
作者
Davis, Steven Q. [1 ]
Garrity, Edward R., Jr. [1 ]
机构
[1] Univ Chicago, Dept Pulm & Crit Care Med, Chicago, IL 60637 USA
关键词
lung allocation score; lung transplantation; organ allocation; organ donation;
D O I
10.1378/chest.07-0011
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Since the first successful single-lung transplant in 1983 and double-lung transplant in 1986, thousands of patients have benefited from the procedures. Until 1995, allocation of donor lungs was based purely on time on the waiting list. In 1995, a 90-day credit was given to patients with idiopathic pulmonary fibrosis, while still maintaining allocation based on waiting list time. In 2005, the lung allocation score (LAS) was implemented, dramatically changing the way lungs are allocated. This article will explore the reasons for the creation of the LAS, the design of the score, early experience with transplant results under the new system, and fut, -ther changes that may be made to the system of lung allocation. As surgical techniques and medical management evolve, so to will the management of potential donors and the allocation of their organs, with the aim of benefiting patients needing lung transplantation in the United Sates.
引用
收藏
页码:1646 / 1651
页数:6
相关论文
共 15 条
[1]   Medical progress - Lung transplantation [J].
Arcasoy, SM ;
Kotloff, RM .
NEW ENGLAND JOURNAL OF MEDICINE, 1999, 340 (14) :1081-1091
[2]   The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease [J].
Celli, BR ;
Cote, CG ;
Marin, JM ;
Casanova, C ;
de Oca, MM ;
Mendez, RA ;
Pinto Plata, V ;
Cabral, HJ .
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 350 (10) :1005-1012
[3]   Development of the new lung allocation system in the United States [J].
Egan, TM ;
Murray, S ;
Bustami, RT ;
Shearon, TH ;
McCullough, KR ;
Edwards, LB ;
Coke, MA ;
Garrity, ER ;
Sweet, SC ;
Heiney, DA ;
Grover, FL .
AMERICAN JOURNAL OF TRANSPLANTATION, 2006, 6 (05) :1212-1227
[4]   Pro/con debate: Lung allocation should be based on medical urgency and transplant survival and not on waiting time [J].
Egan, TM ;
Kotloff, RM .
CHEST, 2005, 128 (01) :407-415
[5]   Ethical issues in thoracic organ distribution for transplant [J].
Egan, TM .
AMERICAN JOURNAL OF TRANSPLANTATION, 2003, 3 (04) :366-372
[6]   Heart and lung transplantation in the United States, 1996-2005 [J].
Garrity, E. R. ;
Moore, J. ;
Mulligan, M. S. ;
Shearon, T. H. ;
Zucker, M. J. ;
Murray, S. .
AMERICAN JOURNAL OF TRANSPLANTATION, 2007, 7 (05) :1390-1403
[7]   Early results of lung transplantation after implementation of the new lung allocation score [J].
Hadjiliadis, D. ;
Ahya, V. N. ;
Christie, J. D. ;
Sager, J. D. ;
Poccbettino, A. ;
Kotloff, R. M. .
JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2006, 25 (02) :S173-S174
[8]   Effects of lung allocation score on waiting list rankings and transplant procedures [J].
Lingaraju, Rajiv ;
Blumenthal, Nancy P. ;
Kotloff, Robert M. ;
Christie, Jason ;
Ahya, Vivek N. ;
Sager, Jeffrey S. ;
Pochettino, Alberto ;
Hadjiliadis, Denis .
JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2006, 25 (09) :1167-1170
[9]   Thoracic organ transplantation in the United States, 1995-2004 [J].
Orens, JB ;
Shearon, TH ;
Freudenburger, RS ;
Conte, JV ;
Bhorade, SM ;
Ardehali, A .
AMERICAN JOURNAL OF TRANSPLANTATION, 2006, 6 (05) :1188-1197
[10]  
*ORG PROC TRANSPL, DEC DON TRANSPL US S