Quorum sensing by the Lyme disease spirochete

被引:25
作者
Stevenson, B [1 ]
von Lackum, K [1 ]
Wattier, RL [1 ]
McAlister, JD [1 ]
Miller, JC [1 ]
Babb, K [1 ]
机构
[1] Univ Kentucky, Coll Med, Dept Microbiol Mol Genet & Immunol, Albert B Chandler Med Ctr MS 415, Lexington, KY 40536 USA
关键词
Borrelia burgdorferi; LuxS; autoinducer; tick; relapsing fever;
D O I
10.1016/S1286-4579(03)00184-9
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The Lyme disease spirochete, Borrelia burgdorferi, utilizes a LuxS/autoinducer-2-dependent quorum sensing mechanism to control a specific subset of bacterial proteins. It is hypothesized that this system facilitates transmission of B. burgdorferi from feeding ticks into warm-blooded hosts. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
引用
收藏
页码:991 / 997
页数:7
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