The phosphatidylserine receptor: a crucial molecular switch?

被引：271

作者：

Henson, PM ^{[1
]}

Bratton, DL ^{[1
]}

Fadok, VA ^{[1
]}

机构：

[1] Natl Jewish Med & Res Ctr, Dept Pediat, Cell Biol Program, Denver, CO 80206 USA

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2001年 / 2卷 / 08期

关键词：

D O I：

10.1038/35085094

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The uptake and removal of necrotic or lysed cells involves inflammation and an immune response, due in part to processes that involve members of the collectin family, surface calreticulin and CD91. Clearance of apoptotic cells, by contrast, does not induce either inflammation or immunity. Could the phosphatidylserine receptor be the molecular switch that determines what the outcome will be?

引用

页码：627 / 633

页数：7

共 59 条

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