Reduced amplitude of the sural nerve sensory action potential in PARK2 patients

被引：26

作者：

Ohsawa, Y

Kurokawa, K

Sonoo, M

Yamada, H

Hemmi, S

Iwatsuki, K

Hagiwara, H

Murakami, T

Shirabe, T

Shimizu, T

Sunada, Y

机构：

[1] Kawasaki Med Sch, Dept Internal Med, Div Neurol, Kurashiki, Okayama 7010192, Japan

[2] Kawasaki Med Sch, Dept Neuropathol, Kurashiki, Okayama, Japan

[3] Teikyo Univ, Sch Med, Dept Neurol & Neurosci, Tokyo 173, Japan

来源：

NEUROLOGY | 2005年 / 65卷 / 03期

基金：

日本学术振兴会;

关键词：

D O I：

10.1212/01.wnl.0000171859.85078.3d

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors performed nerve conduction studies in nine PARK2 and eight idiopathic Parkinson disease patients and found a significant reduction of sural sensory nerve action potential ( SNAP) amplitude in eight PARK2 patients who mostly remained asymptomatic. These data suggest that sensory axonal neuropathy may be a common clinical feature of PARK2 and a reduced amplitude of sural SNAP could be a diagnostic indicator of PARK2.

引用

收藏

页码：459 / 462

页数：4

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