Chromatin remodeling and Rb activity

被引：105

作者：

Harbour, JW ^{[1
]}

Dean, DC

机构：

[1] Washington Univ, Div Mol Oncol, St Louis, MO 63110 USA

[2] Washington Univ, Dept Ophthalmol & Visual Sci, St Louis, MO 63110 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 2000年 / 12卷 / 06期

关键词：

D O I：

10.1016/S0955-0674(00)00152-6

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Progression of cells through the cell cycle is central to normal cell proliferation, and checkpoints that regulate this cycle are targets of tumorigenic mutations. One of these checkpoints is the Rb family of proteins that seems to regulate exit of cells from both G(1) and S phase of the cell cycle. Recent studies have linked the function of the Rb family to chromatin remodeling enzymes.

引用

页码：685 / 689

页数：5

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