Selective binding of cis-1,3,5-cyclohexane tricarboxylic acid vs its epimeric trans isomer by a tripodal amidopyridine receptor;: Crystal structures of the 1:1 complexes

被引：10

作者：

Ballester, P ^{[1
]}

Capó, M

Costa, A

Deyà, PM

Gomila, R

Decken, A

Deslongchamps, G

机构：

[1] Univ Illes Balears, Dept Quim, E-07071 Palma de Mallorca, Spain

[2] Univ New Brunswick, Dept Chem, Fredericton, NB E3B 6E2, Canada

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 02期

关键词：

D O I：

10.1021/ol0069148

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A tripodal tris-amidopyridine receptor forms a 1:1 complex with trans-1,3,5-cyclohexane tricarboxylic acid that is 1 order of magnitude less stable than the one formed with the corresponding cis-triacid epimer, The X-ray crystal structures of the complexes have been determined, confirming the binding geometry derived from NMR data in solution and force field calculations, and its geometrical features are used to explain the observed selectivity.

引用

页码：267 / 270

页数：4

共 19 条

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