Islet transplant: an option for childhood diabetes?

被引：24

作者：

Hathout, E

Lakey, J

Shapiro, J

机构：

[1] Univ Alberta, Roberts Ctr, Clin Res Chair Transplantat, CIHR Wyeth Canada,Clin Islet Transplant Program, Edmonton, AB T6G 2C8, Canada

[2] Loma Linda Univ, Childrens Hosp, Pediat Diabet Ctr, Loma Linda, CA 92350 USA

[3] Loma Linda Univ, Childrens Hosp, Div Endocrinol & Diabet, Loma Linda, CA 92350 USA

[4] Univ Alberta, Clin Islet Isolat Lab, Edmonton, AB T6G 2M7, Canada

来源：

ARCHIVES OF DISEASE IN CHILDHOOD | 2003年 / 88卷 / 07期

关键词：

D O I：

10.1136/adc.88.7.591

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Careful assessment of the safety and efficacy of islet transplantation should guide the selection process of a small number of children with type 1 diabetes who may be eligible for the procedure - some of whom are already receiving immunosuppression because of a previous transplant, others who are scheduled to receive de novo islet alone transplantation because of a life threatening risk of hypoglycemia. The outcomes of these initial investigations are predicted to shape the future boundaries of islet transplantation, diabetes, and transplantation.

引用

页码：591 / 594

页数：4

共 50 条

[1]

Basile F, 2000, AM J MANAG CARE, V6, pS1077

[2]

Bode B W, 2000, Diabetes Technol Ther, V2 Suppl 1, pS43

[3]

Bolli GB, 1998, J PEDIATR ENDOCR MET, V11, P103

[4] Pancreatic stem cells [J].

Bonner-Weir, S ;

Sharma, A .

JOURNAL OF PATHOLOGY, 2002, 197 (04) :519-526

[5] Assessment of intracellular insulin content during all steps of human islet isolation procedure [J].

Brandhorst, H ;

Brandhorst, D ;

Brendel, MD ;

Hering, BJ ;

Bretzel, RG .

CELL TRANSPLANTATION, 1998, 7 (05) :489-495

[6]

Brendel M, 1999, INT ISLET TRANSPLANT, P1

[7]

BRENDEL MD, 2001, INT ISLET TRANSPLANT

[8]

Buse J B, 1998, J Fam Pract, V47, pS29

[9] The impact of the Diabetes Control and Complications Trial and Humalog insulin or glycohemoglobin levels and severe hypoglycemia in type 1 diabetes [J].

Chase, HP ;

Lockspeiser, T ;

Peery, B ;

Shepherd, M ;

MacKenzie, T ;

Anderson, J ;

Garg, SK .

DIABETES CARE, 2001, 24 (03) :430-434

[10]

Dorchy H, 2000, DIABETES METAB, V26, P500

← 1 2 3 4 5 →