Count: evolutionary analysis of phylogenetic profiles with parsimony and likelihood

被引:318
作者
Csuroes, Miklos [1 ]
机构
[1] Univ Montreal, Dept Comp Sci & Operat Res, Montreal, PQ, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
RECONSTRUCTION;
D O I
10.1093/bioinformatics/btq315
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Count is a software package for the analysis of numerical profiles on a phylogeny. It is primarily designed to deal with profiles derived from the phyletic distribution of homologous gene families, but is suited to study any other integer-valued evolutionary characters. Count performs ancestral reconstruction, and infers family-and lineage-specific characteristics along the evolutionary tree. It implements popular methods employed in gene content analysis such as Dollo and Wagner parsimony, propensity for gene loss, as well as probabilistic methods involving a phylogenetic birth-and-death model.
引用
收藏
页码:1910 / 1912
页数:3
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