Facile synthesis of thiolacetates from trichloromethyl compounds

被引：10

作者：

Romero-Ortega, M

Reyes, H

Covarruvias-Zuñiga, A

Cruz, R

Avila-Zarraga, JG

机构：

[1] Univ Autonoma Estado Mexico, Fac Quim, Dept Quim Organ, Mexico City, DF, Mexico

[2] Univ Nacl Autonoma Mexico, Inst Quim, Mexico City 04510, DF, Mexico

[3] Univ Nacl Autonoma Mexico, Fac Quim, Mexico City 04510, DF, Mexico

来源：

SYNTHESIS-STUTTGART | 2003年 / 18期

关键词：

trichloromethyl compounds; thiolacetic acid; sodium thiolacetate; thiolacetate derivatives; nucleophilic substitution;

D O I：

10.1055/s-2003-42463

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new method for the conversion of trichloromethyl compounds into the corresponding thiolacetates by treatment with sodium thiolacetate in the presence of thiolacetic acid is described. This transformation proceeds at room temperature in high yield when a strong electron-withdrawing substituent is attached to the trichloromethyl group.

引用

收藏

页码：2765 / 2767

页数：3

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