Impaired Autophagy Triggers Chronic Pancreatitis: Lessons From Pancreas- Specific Atg5 Knockout Mice

被引：49

作者：

Gukovsky, Ilya

Gukovskaya, Anna S.

机构：

[1] VA Greater Los Angeles Healthcare Syst, Los Angeles, CA USA

[2] Univ Calif Los Angeles, Los Angeles, CA USA

来源：

GASTROENTEROLOGY | 2015年 / 148卷 / 03期

关键词：

INFLAMMATION; TRYPSINOGEN; ACTIVATION; CELLS;

D O I：

10.1053/j.gastro.2015.01.012

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

引用

页码：501 / 505

页数：6

共 28 条

[1]

Pancreatic stellate cells: a starring role in normal and diseased pancreas [J].

Apte, Minoti V. ;

Pirola, Romano C. ;

Wilson, Jeremy S. .

FRONTIERS IN PHYSIOLOGY, 2012, 3

[2]

Choi AMK, 2013, NEW ENGL J MED, V368, P1845, DOI [10.1056/NEJMra1205406, 10.1056/NEJMc1303158]

[3]

Functions of autophagy in normal and diseased liver [J].

Czaja, Mark J. ;

Ding, Wen-Xing ;

Donohue, Terrence M., Jr. ;

Friedman, Scott L. ;

Kim, Jae-Sung ;

Komatsu, Masaaki ;

Lemasters, John J. ;

Lemoine, Antoinette ;

Lin, Jiandie D. ;

Ou, Jing-Hsiung James ;

Perlmutter, David H. ;

Randall, Glenn ;

Ray, Ratna B. ;

Tsung, Allan ;

Yin, Xiao-Ming .

AUTOPHAGY, 2013, 9 (08) :1131-1158

[4]

Impaired Autophagy Induces Chronic Atrophic Pancreatitis in Mice via Sex- and Nutrition-Dependent Processes [J].

Diakopoulos, Kalliope N. ;

Lesina, Marina ;

Woermann, Sonja ;

Song, Liang ;

Aichler, Michaela ;

Schild, Lorenz ;

Artati, Anna ;

Roemisch-Margl, Werner ;

Wartmann, Thomas ;

Fischer, Robert ;

Kabiri, Yashar ;

Zischka, Hans ;

Halangk, Walter ;

Demir, Ihsan Ekin ;

Pilsak, Claudia ;

Walch, Axel ;

Mantzoros, Christos S. ;

Steiner, Joerg M. ;

Erkan, Mert ;

Schmid, Roland M. ;

Witt, Heiko ;

Adamski, Jerzy ;

Alguel, Hana .

GASTROENTEROLOGY, 2015, 148 (03) :626-+

[5]

Impaired Autolysosome Formation Correlates With Lamp-2 Depletion: Role of Apoptosis, Autophagy, and Necrosis in Pancreatitis [J].

Fortunato, Franco ;

Buergers, Heinrich ;

Bergmann, Frank ;

Rieger, Peter ;

Buechler, Markus W. ;

Kroemer, Guido ;

Werner, Jens .

GASTROENTEROLOGY, 2009, 137 (01) :350-360

[6]

Autophagy and pancreatitis [J].

Gukovskaya, Anna S. ;

Gukovsky, Ilya .

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2012, 303 (09) :G993-G1003

[7]

Inflammation, Autophagy, and Obesity: Common Features in the Pathogenesis of Pancreatitis and Pancreatic Cancer [J].

Gukovsky, Ilya ;

Li, Ning ;

Todoric, Jelena ;

Gukovskaya, Anna ;

Karin, Michael .

GASTROENTEROLOGY, 2013, 144 (06) :1199-+

[8]

Involvement of autophagy in trypsinogen activation within the pancreatic acinar cells [J].

Hashimoto, Daisuke ;

Ohmuraya, Masaki ;

Hirota, Masahiko ;

Yamamoto, Akitsugu ;

Suyama, Koichi ;

Ida, Satoshi ;

Okumura, Yuushi ;

Takahashi, Etsuhisa ;

Kido, Hiroshi ;

Araki, Kimi ;

Baba, Hideo ;

Mizushima, Noboru ;

Yamamura, Ken-ichi .

JOURNAL OF CELL BIOLOGY, 2008, 181 (07) :1065-1072

[9]

TLR9 and the NLRP3 Inflammasome Link Acinar Cell Death With Inflammation in Acute Pancreatitis [J].

Hoque, Rafaz ;

Sohail, Muhammad ;

Malik, Ahsan ;

Sarwar, Sherhayar ;

Luo, Yuhuan ;

Shah, Ahsan ;

Barrat, Franck ;

Flavell, Richard ;

Gorelick, Fred ;

Husain, Sohail ;

Mehal, Wajahat .

GASTROENTEROLOGY, 2011, 141 (01) :358-369

[10]

Pathophysiological Role of Autophagy: Lesson from Autophagy-Deficient Mouse Models [J].

Ichimura, Yoshinobu ;

Komatsu, Masaaki .

EXPERIMENTAL ANIMALS, 2011, 60 (04) :329-345

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