Intramolecular carbotitanation reaction of active methane compounds having an unactivated alkyne mediated by TiCl4-Et3N

被引：26

作者：

Kitagawa, O ^{[1
]}

Suzuki, T ^{[1
]}

Inoue, T ^{[1
]}

Taguchi, T ^{[1
]}

机构：

[1] Tokyo Univ Pharm & Life Sci, Hachioji, Tokyo 1920392, Japan

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 40期

关键词：

cyclization; titanium and compounds; cyclopentanes; alkynes;

D O I：

10.1016/S0040-4039(98)01579-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In the presence of TiCl4 and Et3N, intramolecular carbotitanation reaction of active methine compounds having an unactivated 4-alkynyl group proceeds in a highly cis-selective manner to give methylenecyclopentane derivatives in good yields. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：7357 / 7360

页数：4

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