Cyclic alternating pattern (CAP) in normal sleep: polysomnographic parameters in different age groups

被引:117
作者
Parrino, L [1 ]
Boselli, M [1 ]
Spaggiari, MC [1 ]
Smerieri, A [1 ]
Terzano, MG [1 ]
机构
[1] Univ Parma, Ist Neurol, I-43100 Parma, Italy
来源
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY | 1998年 / 107卷 / 06期
关键词
sleep; polysomnography; aging; cyclic alternating pattern; sleep arousal;
D O I
10.1016/S0013-4694(98)00108-4
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Objectives: The present study aimed at offering a standerized database for cyclic alternating pattern (CAP) parameters across representative ages of life. Methods: CAP parameters were quantified in 40 healthy sleepers and polygraphically investigated in a partially sound-proof recording chamber under a standard laboratory setting. Four age groups were investigated (teenagers: 10-19 years; young adults: 20-39 years; middle-aged: 40-59 years; elderly: 60 years). Each group included 10 subjects (5 males and 5 females). Nocturnal recordings were accomplished after adaptation to the sleep laboratory that also served to rule out the presence of sleep-related disorders. The study indicated that CAP is a natural phenomenon of NREM sleep, with specific age-related characteristics across the life cycle. Results: CAP rate in NREM sleep, defined as the percentage ratio of total CAP time to total NREM sleep time, showed a U-shape profile with minimum in young adults (31.9%), maximum in the elderly group (55.3%), and intermediate values in teenagers (43.4%) and in middle-aged subjects (37.5%). The longest duration of CAP cycles was found among the older subjects (31 s). The highest amounts of subtypes Al were identified in teenagers (n = 261), while the highest amounts of A2 and A3 subtypes occurred in the elderly group (n = 183). Across the ages, the level of arousal mostly fluctuated in stages 1 and 3, whereas stage 4 emerged as the most stable NREM stage. Overall, stage 2 better reflected the CAP values referred to as total NREM sleep. Conclusions: The periodic arousal fluctuations reflected by CAP are a natural phenomenon of NREM sleep with specific age-related variations across the life cycle. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:439 / 450
页数:12
相关论文
共 65 条
[1]  
[Anonymous], 1992, SLEEP, V15, P174
[2]  
ARFEL G, 1975, HDB ELECTROENCEPHALO, V12, P5
[3]   QUANTITATIVE DESCRIPTION OF EEG PERIODICITIES DURING STATIONARY SLEEP STAGES [J].
BARCARO, U ;
BIZZARI, M ;
NAVONA, C ;
BONANNI, E ;
MURRI, L .
JOURNAL OF SLEEP RESEARCH, 1994, 3 (04) :214-222
[4]   TONUS SYMPATHIQUE ET ACTIVITE ELECTRIQUE CORTICALE [J].
BONVALLET, M ;
DELL, P ;
HIEBEL, G .
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1954, 6 (01) :119-144
[5]  
Boselli M, 1998, SLEEP, V21, P351
[6]   EVOKED K-COMPLEXES AND CARDIOVASCULAR-RESPONSES TO SPINDLE-SYNCHRONOUS AND SPINDLE-ASYNCHRONOUS STIMULUS CLICKS DURING NREM SLEEP [J].
CHURCH, MW ;
JOHNSON, LC ;
SEALES, DM .
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1978, 45 (04) :443-453
[7]  
COOPER R, 1969, ELECTROEN CLIN NEURO, V26, P539
[8]   Electrical reactions of the human brain to auditory stimulation during sleep [J].
Davis, H ;
Davis, PA ;
Loomis, AL ;
Harvey, EN ;
Hobart, G .
JOURNAL OF NEUROPHYSIOLOGY, 1939, 2 (06) :500-514
[9]   EVALUATION OF THE STABILITY AND QUALITY OF SLEEP USING HJORTHS DESCRIPTORS [J].
DEPOORTERE, H ;
FRANCON, D ;
GRANGER, P ;
TERZANO, MG .
PHYSIOLOGY & BEHAVIOR, 1993, 54 (04) :785-793
[10]   Periodic leg movements are part of the B-wave rhythm and the cyclic alternating pattern [J].
Droste, DW ;
Krauss, JK ;
Hagedorn, G ;
Kaps, M .
ACTA NEUROLOGICA SCANDINAVICA, 1996, 94 (05) :347-352