Reversible leukoencephalopathy associated with cerebral amyloid angiopathy

被引:74
作者
Oh, U
Gupta, R
Krakauer, JW
Khandji, AG
Chin, SS
Elkind, MSV
机构
[1] Natl Inst Neurol Disorders & Stroke, Neuroimmunol Branch, Bethesda, MD USA
[2] Cleveland Clin Fdn, Dept Vasc Neurol, Cleveland, OH USA
[3] Columbia Univ, Dept Neurol, New York, NY USA
[4] Columbia Univ, Dept Radiol, New York, NY USA
[5] Columbia Univ, Dept Pathol, New York, NY USA
[6] Columbia Univ Coll Phys & Surg, Sergievsky Ctr, New York, NY 10032 USA
关键词
D O I
10.1212/01.WNL.0000106951.94624.DF
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The authors describe three patients with reversible leukoencephalopathy associated with cerebral amyloid angiopathy (CAA). Rapid progression of neurologic symptoms was followed by dramatic clinical and radiographic improvement. Pathologically, CAA was associated with varying degrees of inflammation ranging from none to transmural granulomatous infiltration. In the appropriate clinical context, the MRI finding of lobar white matter edema with evidence of prior hemosiderin deposition may indicate the presence of a reversible CAA leukoencephalopathy.
引用
收藏
页码:494 / 497
页数:4
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