Why have sustained increases in obesity and type 2 diabetes not offset declines in cardiovascular mortality over recent decades in Western countries?

被引：13

作者：

Capewell, Simon ^{[1
]}

Buchan, Iain ^{[2
]}

机构：

[1] Univ Liverpool, Dept Publ Hlth & Policy, Liverpool L69 3BX, Merseyside, England

[2] Univ Manchester, Sch Community Based Med, Manchester M13 9PL, Lancs, England

来源：

NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES | 2012年 / 22卷 / 04期

基金：

英国医学研究理事会;

关键词：

Obesity; Type; 2; diabetes; Cardiovascular; Mortality; Trends; Western countries; BODY-MASS INDEX; DISEASE; ADULTS; HEALTH; TRENDS; RISK;

D O I：

10.1016/j.numecd.2012.01.005

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The majority of Western countries have reported large falls in cardiovascular diseases (CVD) mortality rates since the 1970s. Yet since the 1980s, they have also experienced two-fold or three-fold increases in the prevalence of obesity and type 2 diabetes - both considered substantial risk factors for CVD. So why have these increasing risks apparently not impacted on CVD mortality falls? This viewpoint outlines the main factors involved; examines recent trends and apparent contradictions; offers some explanations for the trends; discusses how more usefully complex epidemiological models might lead to clearer evidence; offers some explanations for the trends; and explores the implications for CVD prevention. (c) 2012 Elsevier B.V. All rights reserved.

引用

页码：307 / 311

页数：5

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