A rapid-cycling bipolar patient treated with long nights, bedrest, and light

被引：62

作者：

Wirz-Justice, A ^{[1
]}

Quinto, C ^{[1
]}

Cajochen, C ^{[1
]}

Werth, E ^{[1
]}

Hock, C ^{[1
]}

机构：

[1] Univ Basel, Psychiat Klin, Chronobiol & Sleep Lab, CH-4025 Basel, Switzerland

来源：

BIOLOGICAL PSYCHIATRY | 1999年 / 45卷 / 08期

关键词：

rapid-cycling bipolar disorder; extended darkness; sleep; light therapy;

D O I：

10.1016/S0006-3223(98)00289-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Background: Stabilization of rapid-cycling bipolar disorder is extremely difficult. Methods: A refractory bipolar I rapid-cycling patient on valproate was treated with long "nights" (extended sleep in darkness) and daytime light therapy. Results: Rapid cycling immediately stopped on initiation of a 10 hour dark/rest period. This was extended to 14 hours (plus a self-selected I hour midday nap) without problems. Depression gradually improved when midday light therapy was added; near-euthymia was attained after light therapy was shifted to the morning. Conclusions: Nonpharmacological chronobiological treatments may be a means to interrupt rapid cycling. (C) 1999 Society of Biological Psychiatry.

引用

页码：1075 / 1077

页数：3

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