Interface between bone and nacre implants in sheep

被引：152

作者：

Atlan, G

Delattre, O

Berland, S

LeFaou, A

Nabias, G

Cot, D

Lopez, E

机构：

[1] Museum Natl Hist Nat, Lab Physiol Gen & Comparee, CNRS, URA 90, F-75231 Paris 05, France

[2] Univ Montpellier 2, ENSCM, CNRS, UMR 9987,Lab Mat & Procedes Membranaires, Montpellier, France

[3] CHU PZ Quitman, Serv Chirurg Orthoped & Traumatol, Martinique, France

来源：

BIOMATERIALS | 1999年 / 20卷 / 11期

基金：

中国国家自然科学基金;

关键词：

nacre implant; osteogenesis; bone regeneration; X-ray; calcium; phosphorus;

D O I：

10.1016/S0142-9612(98)90212-5

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

We have investigated the interface between bone and chronic implants of nacre in sheep. There was no foreign body reaction over the period of 10 months and the implants were not broken down. Light microscopy indicated activity within an osteoprogenitor cellular layer lining the implant, resulting in a complete sequence of new bone formation. Nacre appeared to bind directly to newly formed bone without any intervening fibrous tissue. Scanning electron microscopy and energy dispersive photon X-microanalysis showed calcium and phosphate ions lining the nacre within the osteoprogenitor tissue. These studies show a dynamic activity of the bone/nacre interface, leading to continuity between the nacre and the bone. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：1017 / 1022

页数：6

共 31 条

[1] Reconstruction of human maxillary defects with nacre powder: histological evidence for bone regeneration [J].