DNA affinity of active alkaloids from Arisarum vulgare Targ.

被引：21

作者：

Melhaoui, A ^{[1
]}

Belouali, H ^{[1
]}

机构：

[1] Univ Mohamed Premier, Fac Sci, Lab Phytochim & Pharmacognosie, Oujda 60000, Morocco

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 1998年 / 62卷 / 01期

关键词：

2-alkylpiperidine alkaloids; 2-alkylpyrrolidine alkaloids; Arisarum vulgare Targ; DNA affinity;

D O I：

10.1016/S0378-8741(98)00052-X

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Some 2-alkylpyrrolidine and 2-alkylpiperidine alkaloids isolated from Arisarum vulgare Targ. demonstrated activity in a high-performance liquid chromatographic system designed to detect compounds capable of interacting with DNA. (-)-R-Bgugaine (N-H), an alkaloid prepared by synthesis, exhibited an important positive response, with total inhibition of DNA absorption at 254 nm. The concentration-dependence of these compounds was determined. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：67 / 71

页数：5

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