Membrane fusion - SNARE the rod, coil the complex

被引：40

作者：

Weis, WI ^{[1
]}

Scheller, RH

机构：

[1] Stanford Univ, Dept Biol Struct, Sch Med, Stanford, CA 94305 USA

[2] Stanford Univ, Dept Cellular & Mol Physiol, Sch Med, Stanford, CA 94305 USA

[3] Stanford Univ, Howard Hughes Med Inst, Sch Med, Stanford, CA 94305 USA

来源：

NATURE | 1998年 / 395卷 / 6700期

关键词：

D O I：

10.1038/26354

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Cellular cargo is transported around the cell in small vesicles that are pinched off the donor membrane and then fuse with the target cell. Fusion is mediated by the interaction of proteins -- found on both the vesicle and target membranes -- called SNAREs. The structure of the core fusion complex has now been solved, and changes our ideas about how this process occurs.

引用

页码：328 / 329

页数：2

共 6 条

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