Characteristics of newly-formed cementum following emdogain application

被引:19
作者
Al-Hezaimi, Khalid [1 ,2 ]
Al-Askar, Mansour [1 ,2 ]
A-Rasheed, Abdulaziz [1 ,2 ]
机构
[1] King Saud Univ, Eng AB Bagshan Growth Factors & Bone Regenerat Re, Riyadh, Saudi Arabia
[2] King Saud Univ, Sch Dent, Dept Periodontol, Riyadh, Saudi Arabia
关键词
regeneration; cementum; enamel matrix protein; ATTACHMENT APPARATUS FORMATION; GUIDED TISSUE REGENERATION; HUMAN INTRABONY DEFECTS; EPITHELIAL ROOT SHEATH; HISTOLOGIC EVALUATION; ENAMEL MATRIX; PERIODONTAL REGENERATION; HUMAN TEETH; PROTEINS; LIGHT;
D O I
10.4248/IJOS11009
中图分类号
R78 [口腔科学];
学科分类号
100302 [口腔临床医学];
摘要
Periodontal regenerative techniques have been proposed; however, the outcomes remain debatable. The present investigation assessed the regenerated cementum following enamel matrix derivative application in dehiscence-type defects. Buccal osseous dehiscences were surgically created on the maxillary cuspid, and the second and fourth premolars in five female beagle dogs. The treatment group (n=15 sites) received the enamel matrix derived application, whereas the control groups (n=15) did not. The dogs were sacrificed 4 months following treatment and the specimens were histologically and histometrically examined. The newly formed cementum was uneven in thickness and mineralization, overlapped the old cementum and exhibited functional orientation, cementocyte lacunae and collagen fibril bundles. Most of the histological specimens showed the presence of a gap between the newly formed cementum and the underlying dentin. Control sites did not exhibit any cementum formation. The present study concluded that newly formed cementum is of cellular type and exhibits multiple characteristics.
引用
收藏
页码:21 / 26
页数:6
相关论文
共 37 条
[1]
Bosshardt DD, 1996, ANAT RECORD, V245, P267
[2]
Effects of enamel matrix proteins on tissue formation along the roots of human teeth [J].
Bosshardt, DD ;
Sculean, A ;
Windisch, P ;
Pjetursson, BE ;
Lang, NP .
JOURNAL OF PERIODONTAL RESEARCH, 2005, 40 (02) :158-167
[3]
INITIAL FORMATION OF CELLULAR INTRINSIC FIBER CEMENTUM IN DEVELOPING HUMAN TEETH - A LIGHT-MICROSCOPIC AND ELECTRON-MICROSCOPIC STUDY [J].
BOSSHARDT, DD ;
SCHROEDER, HE .
CELL AND TISSUE RESEARCH, 1992, 267 (02) :321-335
[4]
HISTOLOGIC COMPARISON OF REGENERATION IN HUMAN INTRABONY DEFECTS WHEN OSTEOGENIN IS COMBINED WITH DEMINERALIZED FREEZE-DRIED BONE ALLOGRAFT AND WITH PURIFIED BOVINE COLLAGEN [J].
BOWERS, G ;
FELTON, F ;
MIDDLETON, C ;
GLYNN, D ;
SHARP, S ;
MELLONIG, J ;
CORIO, R ;
EMERSON, J ;
PARK, S ;
SUZUKI, J ;
MA, S ;
ROMBERG, E ;
REDDI, AH .
JOURNAL OF PERIODONTOLOGY, 1991, 62 (11) :690-702
[5]
BOWERS GM, 1989, J PERIODONTOL, V60, P664, DOI 10.1902/jop.1989.60.12.664
[6]
HISTOLOGIC EVALUATION OF NEW ATTACHMENT APPARATUS FORMATION IN HUMANS .2. [J].
BOWERS, GM ;
CHADROFF, B ;
CARNEVALE, R ;
MELLONIG, J ;
CORIO, R ;
EMERSON, J ;
STEVENS, M ;
ROMBERG, E .
JOURNAL OF PERIODONTOLOGY, 1989, 60 (12) :675-682
[7]
BOWERS GM, 1989, J PERIODONTOL, V60, P683, DOI 10.1902/jop.1989.60.12.683
[8]
Camelo M, 1998, INT J PERIODONT REST, V18, P321
[9]
CLINICAL AND HISTOLOGICAL EVALUATION OF AUTOGENOUS ILIAC BONE GRAFTS IN HUMANS .1. WOUND-HEALING 2 TO 8 MONTHS [J].
DRAGOO, MR ;
SULLIVAN, HC .
JOURNAL OF PERIODONTOLOGY, 1973, 44 (10) :599-613
[10]
GUIDED TISSUE REGENERATION WITH DENTIN BIOMODIFICATION [J].
DYER, BL ;
CAFFESSE, RG ;
NASJLETI, CE ;
MORRISON, EC .
JOURNAL OF PERIODONTOLOGY, 1993, 64 (11) :1052-1060