Enantioselective synthesis of epoxides and aziridines by asymmetric methylidene transfer from a sulfimide to carbonyl compounds and imines

被引：22

作者：

Baird, CP ^{[1
]}

Taylor, PC ^{[1
]}

机构：

[1] Univ Warwick, Dept Chem, Coventry CV4 7AL, W Midlands, England

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1998年 / 20期

关键词：

D O I：

10.1039/a805405c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The sodium salt of sulfimide 2 is a useful asymmetric methylidene transfer agent for the synthesis of enantiomerically enriched epoxides and aziridines. Moderate enantioselectivities are observed with a broad range of carbonyl compounds and with imines. An enantiomerically enriched beta-adrenoreceptor agonist analogue was prepared using the new method.

引用

页码：3399 / 3403

页数：5

共 30 条

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