Toward a neurobiology of psychotherapy: Basic science and clinical applications

被引:125
作者
Etkin, A
Phil, M
Pittenger, C
Polan, HJ
Kandel, ER
机构
[1] Columbia Univ, Med Ctr, Howard Hughes Med Inst, Kavli Inst Brain Sci,Ctr Neurobiol & Behav, New York, NY 10032 USA
[2] Yale Univ, Dept Psychiat, New Haven, CT 06520 USA
[3] Cornell Univ, Weill Med Coll, New York, NY USA
关键词
D O I
10.1176/appi.neuropsych.17.2.145
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Psychotherapy is used commonly to treat a variety of mental illnesses, yet surprisingly little is known about its biological mechanisms especially in comparison with pharmacotherapy. In this review we survey the current knowledge about changes in brain function following psychotherapeutic intervention that are detectable with current neuroimaging techniques. We also consider the possible role for neuroimaging in refining clinical diagnoses and predicting treatment outcome, which would benefit both clinical decision-making and the cognitive neuroscience of psychotherapy.
引用
收藏
页码:145 / 158
页数:14
相关论文
共 64 条
[1]  
Aggleton J.P., 2000, AMYGDALA FUNCTIONAL, V2nd
[2]  
*APA INC, 2000, DIAGN STAT MAN MENT
[3]   Influence of the serotonin transporter promoter gene and shyness on children's cerebral responses to facial expressions [J].
Battaglia, M ;
Ogliari, A ;
Zanoni, A ;
Citterio, A ;
Pozzoli, U ;
Giorda, R ;
Maffei, C ;
Marino, C .
ARCHIVES OF GENERAL PSYCHIATRY, 2005, 62 (01) :85-94
[4]   Children's discrimination of expressions of emotions: Relationship with indices of social anxiety and shyness [J].
Battaglia, M ;
Ogliari, A ;
Zanoni, A ;
Villa, F ;
Citterio, A ;
Binaghi, F ;
Fossati, A ;
Maffei, C .
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 2004, 43 (03) :358-365
[5]  
BAXTER LR, 1992, ARCH GEN PSYCHIAT, V49, P681
[6]   Cognitive behavioural therapy reduces short term rehospitalisation compared with psychoeducation in inpatients with schizophrenia [J].
Bechdolf, A. ;
Knost, B. ;
Kuntermann, C. .
EVIDENCE-BASED MENTAL HEALTH, 2005, 8 (01) :8-8
[7]   An information processing model of anxiety: Automatic and strategic processes [J].
Beck, AT ;
Clark, DA .
BEHAVIOUR RESEARCH AND THERAPY, 1997, 35 (01) :49-58
[8]   Further evidence of association between behavioral inhibition and social anxiety in children [J].
Biederman, J ;
Hirshfeld-Becker, DR ;
Rosenbaum, JF ;
Hérot, C ;
Friedman, D ;
Snidman, N ;
Kagan, J ;
Faraone, SV .
AMERICAN JOURNAL OF PSYCHIATRY, 2001, 158 (10) :1673-1679
[9]   Regional brain metabolic changes in patients with major depression treated with either paroxetine or interpersonal therapy -: Preliminary findings [J].
Brody, AL ;
Saxena, S ;
Stoessel, P ;
Gillies, LA ;
Fairbanks, LA ;
Alborzian, S ;
Phelps, ME ;
Huang, SC ;
Wu, HM ;
Ho, ML ;
Ho, MK ;
Au, SC ;
Maidment, K ;
Baxter, LR .
ARCHIVES OF GENERAL PSYCHIATRY, 2001, 58 (07) :631-640
[10]   FDG-PET predictors of response to behavioral therapy and pharmacotherapy in obsessive compulsive disorder [J].
Brody, AL ;
Saxena, S ;
Schwartz, JM ;
Stoessel, PW ;
Maidment, K ;
Phelps, ME ;
Baxter, LR .
PSYCHIATRY RESEARCH-NEUROIMAGING, 1998, 84 (01) :1-6