Hydroxylated diterpenoids from Halimium viscosum

被引：13

作者：

Rodilla, JML ^{[1
]}

De Mendonça, DIM

Urones, JG

Moro, RF

机构：

[1] Univ Beira Interior, Dept Quim, P-6200 Covilha, Portugal

[2] Univ Salamanca, Dept Quim Organ, E-37008 Salamanca, Spain

来源：

PHYTOCHEMISTRY | 1998年 / 49卷 / 03期

关键词：

Halimium viscosum; Cistaceae; chemotype; labdane; ent-halimane; valparane; valparolane;

D O I：

10.1016/S0031-9422(98)00168-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Several hydroxylated bi- and tri-cyclic terpenoids have been isolated from the aerial parts of Halimium viscosum (Celorico da Beira, Portugal). Together with valparolone, with the same skeleton, two additional compounds have been identified: (4S)-2 beta-acetoxyvalparol-15-en-3-one and (4S)-2 beta-acetoxyvalparol-8(14)-en-3-one. Together with the well-known valpara-3(19),15-dien-2 beta-ol, valpara-1,13-dien-2 alpha-ol and 2 beta-acetoxyvalpara-4,15-dien-3 alpha-ol, two new compounds have been isolated, belonging to the valparane class, and identified as valpara-3,15-dien-2 beta-ol and 3 alpha-hydroxyvalpara-4,15-dien-2-one. There are several bicyclic diterpenoids that should be noted: with labdane skeleton; a diformate and the monoformylderivatives of labd-7-en-3 beta,15-diol and with halimane skeleton the 15-hydroxy-ent-halim-1(10)-en-18,2 beta-olide. The total composition of the aerial parts of this plant allows the identification of Celorico da Beira Halimium viscosum as a new chemotype. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：817 / 822

页数：6

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