Comparative assessment of ureteral stent biomaterial encrustation

被引:108
作者
Tunney, MM
Keane, PF
Jones, DS
Gorman, SP
机构
[1] QUEENS UNIV BELFAST, SCH PHARM, BELFAST BT9 7BL, ANTRIM, NORTH IRELAND
[2] BELFAST CITY HOSP, DEPT UROL, BELFAST BT9 7BL, ANTRIM, NORTH IRELAND
关键词
ureteral stents; encrustation; polyurethanes; silicones; artificial urine;
D O I
10.1016/0142-9612(96)89780-8
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Long-term use of ureteral stents is hindered by the inherent problem of biomaterial encrustation which may lead to stone formation and attendant problems. The wide variety of polymeric biomaterials currently used for stent fabrication suggests that no single material is significantly superior to the others at resisting encrustation. A model representing upper urinary tract conditions was employed to compare the long-term struvite and hydroxyapatite encrustation of five materials currently used in the fabrication of ureteral stents. Silicone was least prone to struvite encrustation, followed by polyurethane, silitek, percuflex and hydrogel-coated polyurethane, in rank order. Similarly, silicone was least prone to hydroxyapatite encrustation, followed by silitek, polyurethane, percuflex and hydrogel-coated polyurethane. This study has shown that the problem of encrustation may limit the long-term use of ureteral stent biomaterials and suggests directions for improvement of biomaterials in this regard. (C) 1996 Eisevier Science Limited.
引用
收藏
页码:1541 / 1546
页数:6
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