Shortened duration of untreated first episode of psychosis: Changes in patient characteristics at treatment

被引:124
作者
Larsen, TK
McGlashan, TH
Johannessen, JO
Friis, S
Guldberg, C
Haahr, U
Horneland, M
Melle, I
Moe, LC
Opjordsmoen, S
Simonsen, E
Vaglum, P
机构
[1] Yale Univ, Dept Psychiat, New Haven, CT 06520 USA
[2] Roskilde Psychiat Hosp, Roskilde, Denmark
[3] Univ Oslo, Rogaland Psychiat Hosp, N-0316 Oslo, Norway
[4] Univ Oslo, Ullevaal Hosp, N-0407 Oslo, Norway
[5] Univ Oslo, Dept Psychiat & Behav Sci, N-0407 Oslo, Norway
关键词
D O I
10.1176/appi.ajp.158.11.1917
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
objective: This study examined whether duration of untreated psychosis can be shortened in patients with first episodes of DSM-IV schizophrenia spectrum disorders and whether shorted duration alters patient appearance at treatment. Method: Two study groups were ascertained in the same Norwegian health care sector: one from 1993-1994 with usual detection methods and one from 1997-1998 with early detection strategies that included education about psychosis. Results: Patients with early detection had a shorter median duration of untreated psychosis by 21.5 weeks than patients with usual detection. The number with psychosis was greater in the early detection group; the number with schizophrenia was less. Early detection patients had more substance abuse and were younger, better adjusted premorbidly, and less ill. Conclusions: Early detection can shorten duration of untreated psychosis and help more patients when they are less severely ill. Given the devastation of psychosis, this is a significant treatment advance.
引用
收藏
页码:1917 / 1919
页数:3
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