The prion protein as a receptor for amyloid-β

被引：215

作者：

Kessels, Helmut W. ^{[1
]}

Nguyen, Louis N. ^{[1
]}

Nabavi, Sadegh ^{[1
]}

Malinow, Roberto ^{[1
]}

机构：

[1] Univ Calif San Diego, Ctr Neural Circuits & Behav, La Jolla, CA 92093 USA

来源：

NATURE | 2010年 / 466卷 / 7308期

关键词：

ALZHEIMERS-DISEASE; NATURAL OLIGOMERS; MEMORY;

D O I：

10.1038/nature09217

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Arising from: J. Laurén et al.Nature457, 1128–1132 (2009)10.1038/nature07761; Laurén et al.reply

引用

页码：E3 / E4

页数：2

共 14 条

[1] Synthetic amyloid-β oligomers impair long-term memory independently of cellular prion protein [J].

Balducci, Claudia ;

Beeg, Marten ;

Stravalaci, Matteo ;

Bastone, Antonio ;

Sclip, Alessandra ;

Biasini, Emiliano ;

Tapella, Laura ;

Colombo, Laura ;

Manzoni, Claudia ;

Borsello, Tiziana ;

Chiesa, Roberto ;

Gobbi, Marco ;

Salmona, Mario ;

Forloni, Gianluigi .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (05) :2295-2300

[2] Natural oligomers of the amyloid-protein specifically disrupt cognitive function [J].

Cleary, JP ;

Walsh, DM ;

Hofmeister, JJ ;

Shankar, GM ;

Kuskowski, MA ;

Selkoe, DJ ;

Ashe, KH .

NATURE NEUROSCIENCE, 2005, 8 (01) :79-84

[3] Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models [J].

Hsia, AY ;

Masliah, E ;

McConlogue, L ;

Yu, GQ ;

Tatsuno, G ;

Hu, K ;

Kholodenko, D ;

Malenka, RC ;

Nicoll, RA ;

Mucke, L .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (06) :3228-3233

[4] AMPAR removal underlies Aβ-induced synaptic depression and dendritic spine loss [J].

Hsieh, Helen ;

Boehm, Jannic ;

Sato, Chihiro ;

Iwatsubo, Takeshi ;

Tomita, Taisuke ;

Sisodia, Sangram ;

Malinow, Roberto .

NEURON, 2006, 52 (05) :831-843

[5] APP processing and synaptic function [J].

Kamenetz, F ;

Tomita, T ;

Hsieh, H ;

Seabrook, G ;

Borchelt, D ;

Iwatsubo, T ;

Sisodia, S ;

Malinow, R .

NEURON, 2003, 37 (06) :925-937

[6] Roles of stargazin and phosphorylation in the control of AMPA receptor subcellular distribution [J].

Kessels, Helmut W. ;

Kopec, Charles D. ;

Klein, Matthew E. ;

Malinow, Roberto .

NATURE NEUROSCIENCE, 2009, 12 (07) :888-U105

[7] Aβ toxicity in Alzheimer's disease:: globular oligomers (ADDLs) as new vaccine and drug targets [J].

Klein, WL .

NEUROCHEMISTRY INTERNATIONAL, 2002, 41 (05) :345-352

[8] Aβ oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease [J].

Lacor, Pascale N. ;

Buniel, Maria C. ;

Furlow, Paul W. ;

Clemente, Antonio Sanz ;

Velasco, Pauline T. ;

Wood, Margaret ;

Viola, Kirsten L. ;

Klein, William L. .

JOURNAL OF NEUROSCIENCE, 2007, 27 (04) :796-807

[9] Diffusible, nonfibrillar ligands derived from Aβ1-42 are potent central nervous system neurotoxins [J].

Lambert, MP ;

Barlow, AK ;

Chromy, BA ;

Edwards, C ;

Freed, R ;

Liosatos, M ;

Morgan, TE ;

Rozovsky, I ;

Trommer, B ;

Viola, KL ;

Wals, P ;

Zhang, C ;

Finch, CE ;

Krafft, GA ;

Klein, WL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (11) :6448-6453

[10] Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers [J].

Lauren, Juha ;

Gimbel, David A. ;

Nygaard, Haakon B. ;

Gilbert, John W. ;

Strittmatter, Stephen M. .

NATURE, 2009, 457 (7233) :1128-U84

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