Conversion of a ketone to a geminal bisacetamide: Synthesis of 1,1-bisacetamidocyclohexane

被引：10

作者：

Davis, MC ^{[1
]}

Stasko, D ^{[1
]}

Chapman, RD ^{[1
]}

机构：

[1] USN, Ctr Weap Div, Dept Res, China Lake, CA 93555 USA

来源：

SYNTHETIC COMMUNICATIONS | 2003年 / 33卷 / 15期

关键词：

bisamide; aminal; ketoaminal;

D O I：

10.1081/SCC-120021988

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of the title compound (6) is described. A key step in the novel sequence is the Hofmann rearrangement of an alpha,alpha-dialkyl-alpha-aminocarboxamide mediated by hypervalent iodine reagent.

引用

页码：2677 / 2684

页数：8

共 17 条

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